Publicações

Nesta página: publicações do ano de 2013

Prof. Dr. Fernando de Queiróz Cunha

  1. Barroso-Sousa, R.; Lobo, R.R.; Mendonça, P.R.; Memória, R.R.; Spiller, F.; Cunha, F.Q. & Pazin-Filho, A. Decreased levels of alpha-1-acid glycoprotein are related to the mortality of septic patients in the emergency department. Clinics (São Paulo), 68(8): 1134-1139, 2013.

  2. Cangussú, S.D.; Souza, C.C.; Castro, M.S.A.; Vieira, L.Q.; Cunha, F.Q.; Afonso, L.C.C. & Arantes, R.M.E. The endogenous cytokine profile and nerve fibre density in mouse ear Leishmania major-induced lesions related to nociceptive thresholds. Exp. Parasitol., 133(2): 193-200, 2013.

  3. Carlos, D.; Spiller, F.; Souto, F.O. Trevelin, S.C.; Borges, V.F.; de Freitas, A.; Alves-Filho, J.C.; Silva, J.S.; Ryffel, B. & Cunha, F.Q. Histamine h2 receptor signaling in the pathogenesis of sepsis: studies in a murine diabetes model. J. Immunol., 191(3): 1373-1382, 2013.

  4. Carregaro, V.; Costa, D.L.; Brodskyn, C.; Barral, A.M.; Barral-Netto, M.; Cunha, F.Q. & Silva, J.S. Dual effect of Lutzomyia longipalpis saliva on Leishmania braziliensis infection is mediated by distinct salina-induced cellular recruitment into BALB/c mice ear. BMC Microbiol., 13:102, 2013.

  5. Carreira, E.U.; Carregaro, V.; Teixeira, M.M.; Moriconi, A.; Aramini, A.; Verri Jr., W.A.; Ferreira, S.H.; Cunha, F.Q. & Cunha, T.M. Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain. Eur. J. Pain, 17(5): 654-663, 2013.

  6. Czaikoski, P.G.; Nascimento, D.C.; Sônego, F.; de Freitas, A.; Turato, W.M.; de Carvalho, M.A.; Santos, R.S.; de Oliveira, G.P.; dos Santos Samary, C.; Tefé-Silva, C.; Alves-Filho, J.C.; Ferreira, S.H.; Rossi, M.A.; Rocco, P.R.; Spiller, F. & Cunha, F.Q. Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis. Shock, 39(4): 389-396, 2013.

  7. De Luca, B.; Xavier-Elsas, P.; Barradas, M.; Luz, R. A.; Queto, T.; Jones, C.; Arruda, M. A.; Cunha, T. M.; Cunha, F. Q. & Gaspar-Elsas, M. I. Essential Roles of PKA, iNOS, CD95/CD95L, and Terminal Caspases in Suppression of Eosinopoiesis by PGE2 and Other cAMP-Elevating Agents. Scientific World Journal., 2013, 208705 (Electronic).

  8. Donate, P.B.; Fornari, T.A.; Macedo, C.; Cunha, T.M.; Nascimento, D.C.B.; Sakamoto-Hojo, E.T.; Donadi, E.A.; Cunha, F.Q. & Passos, G.A. T cell post-transcriptional Mirna-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis. PloS ONE, 8(1): e54803, 2013.

  9. Figueiredo, J.; Ferreira, A.E.; Silva, R.L.; Ulloa, L.; Grieco, P.; Cunha, T.M.; Ferreira, S.H.; Cunha, F.Q. & Kanashiro, A. NDP-MSH inhibits neutrophil migration through nicotinic and adrenergic receptors in experimental peritonitis. Naunyn-Schmiedeberg´s Arch. Pharmacol., 386(4): 311-318, 2013.

  10. Godoi, D. F.; Cardoso, C. R.; Silva, M. J.; Ferraz, D. B.; Provinciatto, P. R.; Cunha Fde, Q.; Da Silva, J. S. & Voltarelli, J. C.: Reappraisal of total body irradiation followed by bone marrow transplantation as a therapy for inflammatory bowel disease. Immunobiol., 218(3): 317-324, 2013.

  11. Guerrero, A.T.; Zaperlon, A.C.; Vieira, S.M.; Pinto, L.G.; Ferreira, S.H.; Cunha, F.Q.; Verri Jr., W.A.; & Cunha, T.M. The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia. Naunyn-Schmiedeberg´s Arch. Pharmacol., 386(1): 51-59, 2013.

  12. Hohmann, M. S.; Cardoso, R. D.; Pinho-Ribeiro, F. A.; Crespigio, J.; Cunha, T. M.; Alves-Filho, J. C.; Da Silva, R. V.; Pinge-Filho, P.; Ferreira, S. H.; Cunha, F. Q.; Casagrande, R. & Verri, W. A., Jr.: 5-lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality. Biomed. Res. Int., 2013 627046. (Electronic).

  13. Magro, D.A.C.; Hohmann, M.S.N.; Mizokami, S.S.; Cunha, T.M.; Alves-Filho, J.C.; Casagrande, R.; Ferreira, S.H.; Liew, F.Y.; Cunha, F.Q. & Verri Jr, W.A. An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice. Braz. J. Med. Biol. Res., 46(7): 601-606, 2013.

  14. Petinatti Pavarini, D.; Nogueira, E. F.; Callejon, D. R.; Soares, D. M.; De Souza, G. E.; Cunha Fde, Q.; Lopes, J. L. & Lopes, N. P.: Novel bisabolane derivative from "arnica-da-serra" (Vernonieae: Asteraceae) reduces pro-nociceptive cytokines levels in LPS-stimulated rat macrophages. J. Ethnopharmacol., 148(3): 993-998, 2013.

  15. Pinto, A. C.; Cordeiro Rde, A.; Sidrim, J. J.; Leite, A. K.; Leite, A. C.; Girao, V. C.; Brilhante, R. S.; Rocha, M. F.; Cunha Fde, Q. & Rocha, F. A.: Anti-inflammatory and immunomodulatory effect of an extract of Coccidioides posadasii in experimental arthritis. Mycopathologia, 175(3-4): 193-206, 2013.

  16. Polli-Lopes, A.C.; Estofolete, C.F.; Oliani, S.M.; Zucoloto, S.; Cunha, F.Q. & Gil, C.D. Myenteric denervation in gastric carcinogenesis: differential modujlation of nitric oxide and annexin-A1. Int. J. Clin. Exp. Pathol., 6(1): 13-23, 2013.

  17. Saia, R.S.; Bertozi, G.; Mestriner, F.L.; Antunes-Rodrigues, J.; Queiroz Cunha, F.; Cárnio, E.C. Cardiovascular and infflammatory response to cholecystokinin during endotoxemic shock. Shock, 39(1): 1004-1013, 2013.

  18. Soares, P.M.G.; Mota, J.M.S.C.; Souza, E.P.; Justino, P.F.C.; Franco, A.X.; Cunha, F.Q.; Ribeiro, R.A. & Souza, M.H.L.P. Inflammatory intestinal damage induced by 5-fluorouracil requires IL-4. Cytokine, 61(1): 46-49, 2013.

  19. Souza, G.R.; Talbot, J.; Lotufo, C.M.; Cunha, F.Q.; Cunha, T.M. & Ferreira, S.H. Fractalkine mediates inflammatory pain through activation of satellite glial cells. Proc. Natl. Acad. Sci. USA., 110(27): 11193-11198, 2013.

  20. Tristão, F.S.M.; Rocha, F.A.; Moreira, A.P.; Cunha, F.Q.; Rossi, M.A. & Silva, J.S. 5-Lipoxygenase activity increases susceptibility to experimental Paracoccidioides brasiliensis infection. Infection and Immunity, 81(4): 1256-1266, 2013.

  21. Vercelino, R.; Cunha, T.M.; Ferreira, E.S.; Cunha, F.Q.; Ferreira, S.H. & Oliveira, M.G. Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel. J. Mater Sci: Mater Med., 24(9): 2157-2169, 2013.

  22. Villarreal, C. F.; Funez, M. I.; Cunha Fde, Q.; Parada, C. A. & Ferreira, S. H. The long-lasting sensitization of primary afferent nociceptors induced by inflammation involves prostanoid and dopaminergic systems in mice. Pharmacol. Biochem. Behav., 103(3): 678-683, 2013.

  23. Yaochite, J.N.U.; Caliari-Oliveira, C.; Davanso, M.R.; Carlos, D.; Malmegrim, K.C.R.; Cardoso, C.R.B.; Ramalho, L.N.Z.; Palma, P.V.B.; Silva, J.S.; Cunha, F.Q.; Covas, D.T. & Voltarelli, J.C. Dynamic changes of the Th17/Tc17 and regulatory T cell populations interfere in the experimental autoimmune diabetes pathogenesis. Immunobiol., 218(3): 338-352, 2013.

  24. Zarpelon, A. C.; Cunha, T. M.; Alves-Filho, J. C.; Pinto, L. G.; Ferreira, S. H.; Mcinnes, I. B.; Xu, D.; Liew, F. Y.; Cunha, F. Q. & Verri, W. A., Jr. IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2. Br. J. Pharmacol., 169(1): 90-101, 2013.

  25. Zarpelon, A.C.; Souza, G.R.; Cunha, T.M.; Schivo, I.R.S.; Marchesi, M.; Casagrande, R.; Pinge-Filho, P.; Cunha, F.Q.; Ferreira, S.H.; Miranda, K.M. & Verri Jr., W.A. The nitroxyl donor, Angeli´s salt, inhibits inflammatory hyperalgesia in rats. Neuropharmacol., 71: 1-9, 2013.

Prof. Dr. Fernando Morgan de Aguiar Corrêa

  1. Alves, F.H.F.; Gomes, F.V.; Reis, D.G.; Crestani, C.C.; Corrêa, F.M.A.; Guimarães, F.S. & Resstel, L.B.M. Involvement of the insular cortex in the consolidation and expression of contextual fear conditioning. Eur. J. Neurosci., 38(2): 2300-2307, 2013.

  2. Busnardo, C.; Alves, F.H.F.; Crestani, C.C.; Scopinho, A.A.; Resstel, L.B.M. & Corrêa, F. M. A. Paraventricular nucleus of the hypothalamus glutamate neurotransmission modulates autonomic, neuroendocrine and behavioral responses to acute restraint stress in rats. Eur. Neuropsychopharmacol., 23(11): 1611-1622, 2013.

  3. Busnardo, C.; Ferreira-Junior, N.C.; Cruz, J.C.; Machado, B.H.; Corrêa, F.M.A. & Resstel, L.B.M. Cardiovascular responses to ATP microinjected into the paraventricular nucleus are mediated by nitric oxide and NMDA glutamate receptors in awake rats. Exp. Physiol., 98(10): 1411-1421, 2013.

  4. Camargo, L.H.A.; Alves, F.H.F.; Biojone, C.; Corrêa, F.M.A.; Resstel, L.B.M. & Crestani, C.C. Involvement of N-methyl-D-aspartate glutamate receptor and nitric oxide in cardiovascular responses to dynamic exercise in rats. Eur. J. Pharmacol., 713(1-3): 16-24, 2013.

  5. Crestani, C.C.; Alves, F.H.F.; Gomes, F.V.; Resstel, L.B.M.; Corrêa, F.M.A. & Herman, J.P. Mechanisms in the bed nucleus of the stria terminalis involved in control of autonomic and neuroendocrine functions: a review. Curr. Neuropharmacol., 11(2): 141-159, 2013.

  6. Da Silva, A.L.; Ruginsk, S.G.; Uchoa, E.T.; Crestani, C.C.; Scopinho, A.A.; Corrêa, F.M.A.; De Martinis, B.S.; Elias, L.L.K.; Resstel, L.B.M. & Antunes-Rodrigues, J. Time-course of neuroendocrine changes and its correlation with hypertension induced by ethanol consumption. Alcohol Alcohol., 48(4): 495-504, 2013.

  7. De Freitas, R.L.; Bolognesi, L.I.; Twardowschy, A.; Corrêa, F.M.A.; Sibson, N. R. & Coimbra, N.C. Neuroanatomical and neuropharmacological approaches to postictal antinociception-related prosencephalic neurons: the role of muscarinic and nicotinic cholinergic receptors. Brain Behav., 3(3): 286-301, 2013.

  8. Deolindo, M.V.; Reis, D.G.; Crestani, C.C.; Tavares, R.F.; Resstel, L.B.M. & Corrêa, F.M.A. NMDA receptors in the lateral hypothalamus have an inhibitory influence on the tachycardiac response to acute restraint stress in rats. Eur. J. Neurosci., 38(3): 2374-2381, 2013.

  9. Gomes, F.V.; Alves, F.H.F.; Guimarães, F.S.; Corrêa, F.M.A.; Resstel, L.B.M. & Crestani, C.C. Cannabidiol administration into the bed nucleus of the stria terminalis alters cardiovascular responses induced by acute restraint stress through 5-HT1A receptor. Eur. Neuropsychopharmacol., 23(9): 1096-1104, 2013.

  10. Guethe, L.M.; Pelegrini-da-Silva, A.; Borelli, K.G.; Juliano, M.A.; Pelosi, G.G.; Pesquero, J.B.; Silva, C.L.M.; Corrêa, F.M.A.; Murad, F.; Prado, W.A. & Martins, A.R. Angiotensin (5-8) modulates nociception at the rat periaqueductal gray via the NO-sGC pathway and an endogenous opioid. Neuroscience, 231: 315-327, 2013.

  11. Lopes-Azevedo, S.; Busnardo, C. & Corrêa, F.M.A. Mechanism of the cardiovascular response caused by L-proline microinjected into the supraoptic nucleus of the hypothalamus in unanesthetized rats. Amino Acids, 45(4): 797-810, 2013.

  12. Pernomian, L.; Gomes, M.S.; Corrêa, F.M.A.; Restini, C.B.A.; Ramalho, L.N.Z. & De Oliveira, A. M. Diabetes confers a vasoprotective role to the neurocompensatory response elicited by carotid balloon injury: consequences on contralateral carotid tone and blood flow. Eur. J. Pharmacol., 708(1-3): 124-138, 2013.

  13. Santini, C.O.; Fassini, A.; Scopinho, A.A.; Busnardo, C.; Corrêa, F.M.A. & Resstel, L.B.M. The ventral hippocampus NMDA receptor/nitric oxide/guanylate cyclase pathway modulates cardiovascular responses in rats. Auton. Neurosci.: Basic & Clin., 177(2): 244-252, 2013.

  14. Scopinho, A.A.; Lisboa, S.F.S.; Guimarães, F.S.; Corrêa, F.M.A.; Resstel, L.B.M. & Joca, S.R.L. Dorsal and ventral hippocampus modulate autonomic responses but not behavioral consequences associated to acute restraint stress in rats. PLoS One, 8(10): e77750, 10 pages, 2013.

Prof. Dr. Francisco Silveira Guimarães

  1. Aguiar, D.C.; Hott, S.C.; Deolindo, M.V.; Guimarães, F.S. & Resstel, L.B.M. The dorsolateral periaqueductal grey N-methyl-D-aspartate/nitric oxide/cyclic guanosine monophosphate pathway modulates the expression of contextual fear conditioning in rats. J. Psychopharmacol., 2013, in press.

  2. Almeida-Santos, A.F.; Gobira, P.H.; Rosa, L.C.; Guimarães, F.S.; Moreira, F.A. & Aguiar, D.C. Modulation of anxiety-like behavior by the endocannabinoid 2-arachidonoylglycerol (2-AG) in the dorsolateral periaqueductal gray. Behav. Brain Res., 252: 10-17, 2013.

  3. Almeida-Santos, A.F.; Moreira, F.A.; Guimarães, F.S. & Aguiar, D.C. Role of TRPV1 receptors on panic-like behaviors mediated by the dorsolateral periaqueductal gray in rats. Pharmacol. Biochem. Behav., 105: 166-172, 2013.

  4. Alves, F.H.F.; Gomes, F.V.; Reis, D.G.; Crestani, C.C.; Corrêa, F.M.A.; Guimarães, F.S. & Resstel, L.B.M. Involvement of the insular cortex in the consolidation and expression of contextual fear conditioning. Eur. J. Neurosci., 38(2): 2300-2307, 2013.

  5. Batalla, A.; Crippa, J.A.; Busatto, G.F.; Guimarães, F.S.; Zuardi, A.W.; Valverde, O.; Atakan, Z.; McGuire, P.K.; Bhattacharyya, S.; Martin-Santos, R. Neuroimaging studies of acute effects of THC and CBD in humans and animals: A systematic review. Curr. Pharm. Dês., 2013, in press.

  6. Campos, A.C.; Soares, V.P.; Carvalho, M.C.; Ferreira, F.R.; Vicente, M.A.; Brandão, M.L.; Zuardi, A.W.; Zangrossi, H., Jr. & Guimarães, F.S. Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats. Psychopharmacol., 226(1): 13-24, 2013.

  7. Campos, A.C.; Ferreira, F.R.; Da Silva, W. A., Jr. & Guimarães, F.S. Predator threat stress promotes long lasting anxiety-like behaviors and modulates synaptophysin and CB1 receptors expression in brain areas associated with PTSD symptoms. Neurosci. Lett., 533: 34-38, 2013.

  8. Campos, A.C.; Fogaça, M.V.; Aguiar, D.C. & Guimarães, F.S. Animal models of anxiety disorders and stress. Rev. Bras. Psiquiatr., 35(Suppl 2): S101-S111, 2013.

  9. Campos, A.C.; Ortega, Z.; Palazuelos, J.; Fogaça, M.V.; Aguiar, D.C.; Diaz-Alonso, J.; Ortega-Gutiérrez, S.; Vázquez-Villa, H.; Moreira, F.A.; Guzmán, M.; Galve-Roperh, I. & Guimarães, F.S. The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system. Int. J. Neuropsychopharmacol., 16(6): 1407-1419, 2013.

  10. Campos, A.C.; Piorino, E.M.; Ferreira, F.R. & Guimarães, F.S. Increased nitric oxide-mediated neurotransmission in the medial prefrontal cortex is associated with the long lasting anxiogenic-like effect of predator exposure. Behav. Brain Res., 256: 391-397, 2013.

  11. Fogaça, M.V.; Galve-Roperh, I.; Guimarães, F.S. & Campos, A.C. Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link? Curr Neuropharmacol., 11(3): 263-275, 2013.

  12. Fogaça, M.V.; Gomes, F.V.; Moreira, F.A.; Guimarães, F.S. & Aguiar, D.C. Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. Psychopharmacol., 226(3): 579-587, 2013.

  13. Gomes, F.V.; Alves, F.H.F.; Guimarães, F.S.; Corrêa, F.M.A.; Resstel, L.B.M. & Crestani, C.C. Cannabidiol administration into the bed nucleus of the stria terminalis alters cardiovascular responses induced by acute restraint stress through 5-HT1A receptor. Eur. Neuropsychopharmacol., 23(9): 1096-1104, 2013.

  14. Gomes, F.V.; Del Bel, E.A. & Guimarães, F.S. Cannabidiol attenuates catalepsy induced by distinct pharmacological mechanisms via 5-HT1A receptor activation in mice. Prog. Neuropsychopharmacol. Biol. Psychiatry, 46: 43-47, 2013.

  15. Lisboa, S.F.; Magesto, A.C.; Aguiar, J.C.; Resstel, L.B.M. & Guimarães, F.S. Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats. Neuropharmacol., 75: 86-94, 2013.

  16. Nardo, M.; Casarotto, P.C.; Gomes, F.V. & Guimarães, F.S. Cannabidiol reverses the mCPP-induced increase in marble-burying behavior. Fundam. Clin. Pharmacol., 2013, in press.

  17. Pereira, V.S.; Casarotto, P.C.; Hiroaki-Sato, V.A.; Sartim, A.G.; Guimarães, F.S. & Joca, S.R.L.: Antidepressant- and anticompulsive-like effects of purinergic receptor blockade: involvement of nitric oxide. Eur. Neuropsychopharmacol., 23(12): 1769-1778, 2013.

  18. Perez, M.; Benitez, S.U.; Cartarozzi, L.P.; Del Bel, E.A.; Guimarães, F.S. & Oliveira, A.L.R. Neuroprotection and reduction of glial reaction by cannabidiol treatment after sciatic nerve transection in neonatal rats. Eur. J. Neurosci., 38(10): 3424-3434, 2013.

  19. Scopinho, A.A.; Lisboa, S.F.S.; Guimarães, F.S.; Corrêa, F.M.A.; Resstel, L.B.M. & Joca, S.R.L. Dorsal and ventral hippocampus modulate autonomic responses but not behavioral consequences associated to acute restraint stress in rats. PLoS One, 8(10): e77750, 2013.

  20. Tonelli, D.A.G.; Pereira, M.; Siba, I.P.; Martynhak, B.J.; Correia, D.; Casarotto, P.C.; Biojone, C.; Guimarães, F.S.; Joca, S.R.L. & Andreatini, R. The antimanic-like effect of phenytoin and carbamazepine on methylphenidate-induced hyperlocomotion: role of voltage-gated sodium channels. Fundam. Clin. Pharmacol., 27(6): 650-655, 2013.

Prof. Dr. Gustavo Ballejo Olivera

Rocha JN1, Ballejo G. Nitric oxide metabolites in the lumbosacral spinal cord interstice and cerebrospinal fluid in female rats with acute cyclophosphamide-induced cystitis. An in vivo microdialysis study. Einstein (Sao Paulo) 11(1): 88-94, 2013.

Prof. Dr. Hélio Zangrossi Júnior

  1. Andrade, T.G.C.S.; Zangrossi, H., Jr. & Graeff, F.G.: The median raphe nucleus in anxiety revisited. J. Psychopharmacol., 27(12): 1107-1115, 2013.

  2. Campos, A.C.; Soares, V.P.; Carvalho, M.C.; Ferreira, F.R.; Vicente, M.A.; Brandão, M.L.; Zuardi, A.W.; Zangrossi, H., Jr. & Guimarães, F.S. Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats. Psychopharmacol., 226(1): 13-24, 2013.

  3. De Bortoli, V.C.; Yamashita, P.S.M. & Zangrossi, H., Jr. 5-HT1A and 5-HT2A receptor control of a panic-like defensive response in the rat dorsomedial hypothalamic nucleus. J. Psychopharmacol., 27(12): 1116-1123, 2013.

  4. Moreira, F.A.; Gobira, P.H.; Viana, T.G.; Vicente, M.A.; Zangrossi, H. & Graeff, F. G. Modeling panic disorder in rodents. Cell. Tissue Res., 354(1): 119-125, 2013.

  5. Roncon, C.M.; Biesdorf, C.; Coimbra, N.C.; Audi, E.A.; Zangrossi, H., Jr. & Graeff, F.G.: Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and µ-receptors. J. Psychopharmacol., 27(12): 1141-1148, 2013.

  6. Strauss, C.V.A.; Vicente, M.A. & Zangrossi, H., Jr. Activation of 5-HT1A receptors in the rat basolateral amygdala induces both anxiolytic and antipanic-like effects. Behav. Brain Res., 246: 103-110, 2013.

Prof. Dr. José Carlos Farias Alves Filho

  1. Carlos, D.; Spiller, F.; Souto, F.O. Trevelin, S.C.; Borges, V.F.; de Freitas, A.; Alves-Filho, J.C.; Silva, J.S.; Ryffel, B. & Cunha, F.Q. Histamine h2 receptor signaling in the pathogenesis of sepsis: studies in a murine diabetes model. J. Immunol., 191(3): 1373-1382, 2013.

  2. Czaikoski, P.G.; Nascimento, D.C.; Sônego, F.; de Freitas, A.; Turato, W.M.; de Carvalho, M.A.; Santos, R.S.; de Oliveira, G.P.; dos Santos Samary, C.; Tefé-Silva, C.; Alves-Filho, J.C.; Ferreira, S.H.; Rossi, M.A.; Rocco, P.R.; Spiller, F. & Cunha, F.Q. Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis. Shock, 39(4): 389-396, 2013.

  3. Garcia, C.C.; Weston-Davies, W.; Russo, R.C.; Tavares, L.P.; Rachid, M.A.; Alves-Filho, J.C.; Machado, A.V.; Ryffel, B.; Nunn, M.A. & Teixeira, M.M. Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury. PLoS ONE, 8(5): e64443, 2013.

  4. Hohmann, M. S.; Cardoso, R. D.; Pinho-Ribeiro, F. A.; Crespigio, J.; Cunha, T. M.; Alves-Filho, J. C.; Da Silva, R. V.; Pinge-Filho, P.; Ferreira, S. H.; Cunha, F. Q.; Casagrande, R. & Verri, W. A., Jr.: 5-lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality. Biomed. Res. Int., 2013 627046. (Electronic)

  5. Magro, D.A.C.; Hohmann, M.S.N.; Mizokami, S.S.; Cunha, T.M.; Alves-Filho, J.C.; Casagrande, R.; Ferreira, S.H.; Liew, F.Y.; Cunha, F.Q. & Verri Jr, W.A. An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice. Braz. J. Med. Biol. Res., 46(7): 601-606, 2013.

  6. Niedbala, W.; Besnard, A.G.; Jiang, H.R.; Alves-Filho, J.C.; Fukada, S.Y.; Nascimento, D.; Mitani, A.; Pushparaj, P.; Alqahtani, M.H. & Liew, F.Y. Nitric oxide-induced regulatory T cells inhibit Th17 but not Th1 cell differentiation and function. J. Immunol., 191(1): 164-170, 2013.

  7. Sesti-Costa, R.; Silva, G.K.; Proença-Módena, J.L.; Carlos, D.; Silva, M.L.; Alves-Filho, J.C.; Arruda, E.; Liew, F.Y. & Silva, J.S. The IL-33/ST2 pathway controls coxsackievirus B5-induced experimental pancreatitis. J. Immunol., 191(1): 283-292, 2013.

  8. Zarpelon, A. C.; Cunha, T. M.; Alves-Filho, J. C.; Pinto, L. G.; Ferreira, S. H.; Mcinnes, I. B.; Xu, D.; Liew, F. Y.; Cunha, F. Q. & Verri, W. A., Jr. IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2. Br. J. Pharmacol., 169(1): 90-101, 2013.

Prof. Dr. José Eduardo Tanus dos Santos

  1. Amaral, J.H.; Montenegro, M.F.; Pinheiro, L.C.; Ferreira, G.C.; Barroso, R.P.; Costa-Filho, A.J. & Tanus-Santos, J. E. TEMPOL enhances the antihypertensive effects of sodium nitrite by mechanisms facilitating nitrite-derived gastric nitric oxide formation. Free Radic. Biol. Med., 65: 446-455, 2013.

  2. Amaral, L.M.; Pinheiro, L.C.; Guimarães, D.A.; Palei, A.C.; Sertório, J.T.; Portella, R.L. & Tanus-Santos, J. E. Antihypertensive effects of inducible nitric oxide synthase inhibition in experimental pre-eclampsia. J. Cell. Mol. Med., 20 (10): 1300-1307, 2013.

  3. Andrade, V.L.; Sertório, J.T.; Eleuterio, N.M.; Tanus-Santos, J.E.; Fernandes, K.S. & Sandrim, V.C. Simvastatin treatment increases nitrite levels in obese women: Modulation by-786C polymorphism of eNOS. Nitric Oxide, 33: 83-87, 2013.

  4. Belo, V.A.; Luizon, M.R.; Carneiro, P.C.; Gomes, V.A.; Lacchini, R.; Lanna, C.M.; Souza-Costa, D.C. & Tanus-Santos, J. E. Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity. Mol. Biol. Rep., 40(3): 2697-2704, 2013.

  5. Belo, V.A.; Souza-Costa, D.C.; Lacchini, R.; Seertório, J.T.C; Lanna, C.M.; Carmo, V.P. & Tanus-Santos, J.E. Adiponectin associates positively with nitrite levels in children and adolescents. Int. J. Obes., 37(5): 740-743, 2013.

  6. Castro, M.M. & Tanus-Santos, J.E. Inhibition of matrix metalloproteinases (MMPs) as a potential strategy to ameliorate hypertension-induced cardiovascular alterations. Curr. Drug Targets, 14(3): 335-343, 2013.

  7. Cáu, S.B.A.; Barato, R.C.; Celes, M.R.; Muniz, J.J.; Rossi, M.A. & Tanus-Santos, J. E. Doxycycline prevents acute pulmonary embolism-induced mortality and right ventricular deformation in rats. Cardiovasc. Drugs Ther., 27(4): 259-267, 2013.

  8. Ceron, C.S.; Rizzi, E.; Guimarães, D.A.; Martins-Oliveira, A.; Gerlach, R.F. & Tanus-Santos, J.E. Nebivolol attenuates prooxidant and profibrotic mechanisms involving TGF-β and MMPs, and decreases vascular remodeling in renovascular hypertension. Free Radic. Biol. Med., 65: 47-56, 2013.

  9. Eleutério, N.M.; Palei, A.C.T.; Machado, J.S.R.; Tanus-Santos, J.E.; Cavalli, R.C. & Sandrim, V.C. Relationship between adiponectin and nitrite in healthy and preeclampsia pregnancies. Clin. Chim. Acta, 423: 112-115, 2013.

  10. Ferraz, K.C.; Sousa-Santos, O.; Neto-Neves, E.M.; Rizzi, E.; Muniz, J.J.; Gerlach, R.F. & Tanus-Santos, J.E. Recombinant human matrix metalloproteinase-2 impairs cardiovascular β-adrenergic responses. Basic Clin. Pharmacol. Toxicol., 112(2): 103-109, 2013.

  11. Gomes, H.F.; Palei, A.C.T.; Machado, J.S.R.; Da Silva, L.M.; Montenegro, M.F.; Jordão, A.A.; Duarte, G.; Tanus-Santos, J.E.; Cavalli, R.C. & Sandrim, V.C. Assessment of oxidative status markers and NO bioavailability in hypertensive disorders of pregnancy. J. Hum. Hypertens., 27(6): 345-348, 2013.

  12. Gonçalves, F.M.; Martins-Oliveira, A.; Lacchini, R.; Belo, V.A.; Speciali, J.G.; Dach, F. & Tanus-Santos, J.E. Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura. Gene, 512(1): 35-40, 2013.

  13. Guimarães, D.A.; Rizzi, E.; Ceron, C.S.; Pinheiro, L.C.; Gerlach, R.F. & Tanus-Santos, J.E. Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension. Redox Biol.,1(1): 578-585, 2013.

  14. Lacchini, R.; Muniz, J.J.; Nobre, Y.T.; Cologna, A.J.; Martins, A.C. & Tanus-Santos, J.E. VEGF genetic polymorphisms affect the responsiveness to sildenafil in clinical and postoperative erectile dysfunction. Pharmacogenomics J., 13(5): 437-442, 2013.

  15. Leite, L.N.; Lacchini, R.; Carnio, E.C.; Queiroz, R.H.; Tanus-Santos, J.E.; de Oliveira, A.M. & Tirapelli, C.R. Ethanol consumption increases endothelin-1 expression and reactivity in the rat cavernosal smooth muscle. Alcohol Alcohol., 48(6): 657-666, 2013.

  16. Malvezzi, H.; Aguiar, V.G.; Paz, C.C.P.; Tanus-Santos, J.E.; Penna, I.A.A. & Navarro, P.A. Increased circulating MMP-2 levels in infertile patients with moderate and severe pelvic endometriosis. Reprod. Sci., 20(5): 557-562, 2013.

  17. Martins-Oliveira, A.; Castro, M.M.; Oliveira, D.M.M.; Rizzi, E.; Ceron, C.S.; Guimarães, D.; Reis, R.I.; Costa-Neto, C.M.; Casarini, D.E.; Ribeiro, A.A.; Gerlach, R.F. & Tanus-Santos, J.E. Contrasting effects of aliskiren versus losartan on hypertensive vascular remodeling. Int. J. Cardiol., 167(4): 1199-1205, 2013.

  18. Meschiari, C.A.; Izidoro-Toledo, T.; Gerlach, R.F. & Tanus-Santos, J.E. Nitric oxide attenuates matrix metalloproteinase-9 production by endothelial cells independent of cGMP- or NFκB-mediated mechanisms. Mol. Cell. Biochem., 378(1-2): 127-135, 2013.

  19. Meschiari, C.A.; Marcaccini, A.M.; Moura, B.C.S.; Zuardi, L.R.; Tanus-Santos, J.E. & Gerlach, R.F. Salivary MMPs, TIMPs, and MPO levels in periodontal disease patients and controls. Clin. Chim. Acta, 421: 140-146, 2013.

  20. Metzger, I.F.; Luizon, M.R.; Lacchini, R.; Ishizawa, M.H. & Tanus-Santos, J.E. Effects of endothelial nitric oxide synthase tagSNPs haplotypes on nitrite levels in black subjects. Nitric Oxide, 28: 33-38, 2013.

  21. Miranda, J.A.; Belo, V.A.; Souza-Costa, D.C.; Lanna, C.M.M. & Tanus-Santos, J.E. eNOS polymorphism associated with metabolic syndrome in children and adolescents. Mol. Cell. Biochem., 372(1-2): 155-160, 2013.

  22. Miyague, A.H.; Martins, W.P.; Machado, J.S.R.; Palei, A.C.; Amaral, L.M.; Teixeira, D.M.; Sandrim, V.C.; Sertório, J.T.C.; Tanus-Santos, J.E.; Duarte, G. & Cavalli, R.C. Maternal flow-mediated dilation and nitrite concentration during third trimester of pregnancy and postpartum period. Hypertens. Pregnancy, 32(3): 225-234, 2013.

  23. Muniz, J.J.; Lacchini, R.; Rinaldi, T.O.; Nobre, Y.T.D.A.; Cologna, A.J.; Martins, A.C.P. & Tanus-Santos, J.E. Endothelial nitric oxide synthase genotypes and haplotypes modify the responses to sildenafil in patients with erectile dysfunction. Pharmacogenomics J., 13(2): 189-196, 2013.

  24. Muniz, J.J.; Lacchini, R.; Sertório, J.T.C.; Jordão, A.A., Jr.; Nobre, Y.T.D.A.; Tucci, S., Jr.; Martins, A.C.P. & Tanus-Santos, J.E. Low nitric oxide bioavailability is associated with better responses to sildenafil in patients with erectile dysfunction. Naunyn-Schmiedeberg´s Arch. Pharmacol., 386(9): 805-811, 2013.

  25. Neto-Neves, E.M.; Kiss, T.; Muhl, D. & Tanus-Santos, J.E. Matrix metalloproteinases as drug targets in acute pulmonary embolism. Curr. Drug Targets, 14(3): 344-352, 2013.

  26. Neto-Neves, E.M.; Sousa-Santos, O.; Ferraz, K.C.; Rizzi, E.; Ceron, C.S.; Romano, M.M.D.; Gali, L.G.; Maciel, B.C.; Schulz, R.; Gerlach, R.F. & Tanus-Santos, J.E. Matrix metalloproteinase inhibition attenuates right ventricular dysfunction and improves responses to dobutamine during acute pulmonary thromboembolism. J. Cell. Mol. Med., 17(12): 1588-1597, 2013.

  27. Oliveira-Paula, G.H.; Lacchini, R.; Coeli-Lacchini, F.B.; Moreno Jr., H. & Tanus-Santos, J.E. Inducible nitric oxide synthase haplotype associated with hypertension and responsiveness to antihypertensive drug therapy. Gene, 515(2): 391-395, 2013.

  28. Palei, A.C.T.; Granger, J.P. & Tanus-Santos, J.E. Matrix metalloproteinases as drug targets in preeclampsia. Curr. Drug Targets, 14(3): 325-334, 2013.

  29. Quinaglia, T.; de Faria, A.P.C.; Fontana, V.; Barbaro, N.R.; Sabbatini, A.R.; Sertório, J.T.; Demacq, C.; Tanus-Santos, J.E. & Moreno, H. Acute cardiac and hemodynamic effects of sildenafil on resistant hypertension. Eur. J. Clin. Pharmacol., 69(12): 2027-2036, 2013.

  30. Rizzi, E.; Castro, M.M.; Ceron, C.S.; Neto-Neves, E.M.; Prado, C.M.; Rossi, M.A.; Tanus-Santos, J.E. & Gerlach, R.F. Tempol inhibits TGF-β and MMPs upregulation and prevents cardiac hypertensive changes. Int. J. Cardiol., 165(1): 165-173, 2013.

  31. Rizzi, E.; Ceron, C.S.; Guimarães, D.A.; Prado, C.M.; Rossi, M.A.; Gerlach, R.F. & Tanus-Santos, J.E. Temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and TGF-β in renovascular hypertension-induced cardiac hypertrophy. Exp. Mol. Pathol., 94(1): 1-9, 2013.

  32. Sandrim, V.C.; Luizon, M.R.; Izidoro-Toledo, T.C.; Coelho, E.B.; Moreno, H. Jr. & Tanus-Santos, J.E. Functional VEGF haplotypes affect the susceptibility to hypertension. J. Hum. Hypertens., 27(1): 31-37, 2013.

  33. Sertório, J.T.; Lacchini, R.; Amaral, L.M.; Palei, A.C.T.; Cavalli, R.C.; Sandrim, V.C.; Duarte, G. & Tanus-Santos, J.E. Haptoglobin polymorphism affects nitric oxide bioavailability in preeclampsia. J. Human Hypertens., 27(6): 349-354, 2013.

  34. Sertório, J.T.; Neto-Neves, E.M.; Dias-Junior, C.A.; Sousa-Santos, O.; Kiss, T.; Mühl, D. & Tanus-Santos, J.E. Elevated plasma hemoglobin levels increase nitric oxide consumption in experimental and clinical acute pulmonary thromboembolism. Crit. Care Med., 41(7): e118-e124, 2013.

  35. Silva, B.R.; Pernomian, L.; Grando, M.D.; Amaral, J.H.; Tanus-Santos, J.E. & Bendhack, L.M. Hydrogen peroxide modulates phenylephrine-induced contractile response in renal hypertensive rat aorta. Eur. J. Pharmacol., 721(1-3): 193-200, 2013.

  36. Silva, P.S.; Fontana, V.; Luizon, M.R.; Lacchini, R.; Silva, W.A., Jr.; Biagi, C. & Tanus-Santos, J.E. eNOS and BDKRB2 genotypes affect the antihypertensive responses to enalapril. Eur. J. Clin. Pharmacol., 69(2): 167-177, 2013.

  37. Sousa-Santos, O.; Neto-Neves, E.M.; Ferraz, K.C.; Sertório, J.T.; Portella, R.L. & Tanus-Santos, J.E. The antioxidant tempol decreases acute pulmonary thromboembolism-induced hemolysis and nitric oxide consumption. Thromb. Res., 132(5): 578-583, 2013.

  38. Tanus-Santos, J.E. Matrix metalloproteinases: a target in in-stent restenosis? Cardiol., 124(1): 49-50, 2013.

  39. Tanus-Santos, J.E. Matrix metalloproteinases: Drug targets in cardiovascular diseases (Editorial). Curr. Drug Targets, 14(3): 275, 2013.

  40. Tanus-Santos, J.E. Targeting RV failure and cardiomyocyte injury in acute pulmonary thromboembolism. Nat. Rev. Cardiol., 10(10): 559, 2013.

  41. Tanus-Santos, J.E. Antioxidant effects of phosphodiesterase-5 inhibitors. Cardiovasc. Res., 100(1): 170, 2013.

  42. Trapé, A.A.; Jacomini, A.M.; Muniz, J.J.; Seertório, J.T.C.; Tanus-Santos, J.E.; Amaral, S.L. & Zago, A.S. The relationship between training status, blood pressure and uric acid in adults and elderly. BMC Cardiovasc. Disord., 13: 44, 2013.

Prof. Dr. Leonardo Resstel Barbosa Moraes

  1. Aguiar, D.C.; Hott, S.C.; Deolindo, M.V.; Guimarães, F.S. & Resstel, L.B.M. The dorsolateral periaqueductal grey N-methyl-D-aspartate/nitric oxide/cyclic guanosine monophosphate pathway modulates the expression of contextual fear conditioning in rats. J. Psychopharmacol., 2013, in press.

  2. Alves, F.H.F.; Gomes, F.V.; Reis, D.G.; Crestani, C.C.; Corrêa, F.M.A.; Guimarães, F.S. & Resstel, L.B.M. Involvement of the insular cortex in the consolidation and expression of contextual fear conditioning. Eur. J. Neurosci., 38(2): 2300-2307, 2013.

  3. Borelli, K.G.; Albrechet-Souza, L.; Fedoce, A.G.; Fabri, D.S.; Resstel, L.B.M. & Brandão, M.L. Conditioned fear is modulated by CRF mechanisms in the periaqueductal gray columns. Horm. Behav., 63(5): 791-799, 2013.

  4. Busnardo, C.; Alves, F.H.F.; Crestani, C.C.; Scopinho, A.A.; Resstel, L.B.M. & Corrêa, F. M. A. Paraventricular nucleus of the hypothalamus glutamate neurotransmission modulates autonomic, neuroendocrine and behavioral responses to acute restraint stress in rats. Eur. Neuropsychopharmacol., 23(11): 1611-1622, 2013.

  5. Busnardo, C.; Ferreira-Junior, N.C.; Cruz, J.C.; Machado, B.H.; Corrêa, F.M.A. & Resstel, L.B.M. Cardiovascular responses to ATP microinjected into the paraventricular nucleus are mediated by nitric oxide and NMDA glutamate receptors in awake rats. Exp. Physiol., 98(10): 1411-1421, 2013.

  6. Camargo, L.H.A.; Alves, F.H.F.; Biojone, C.; Corrêa, F.M.A.; Resstel, L.B.M. & Crestani, C.C. Involvement of N-methyl-D-aspartate glutamate receptor and nitric oxide in cardiovascular responses to dynamic exercise in rats. Eur. J. Pharmacol., 713(1-3): 16-24, 2013.

  7. Crestani, C.C.; Alves, F.H.F.; Gomes, F.V.; Resstel, L.B.M.; Corrêa, F.M.A. & Herman, J.P. Mechanisms in the bed nucleus of the stria terminalis involved in control of autonomic and neuroendocrine functions: a review. Curr. Neuropharmacol., 11(2): 141-159, 2013.

  8. Da Silva, A.L.; Ruginsk, S.G.; Uchoa, E.T.; Crestani, C.C.; Scopinho, A.A.; Corrêa, F.M.A.; De Martinis, B.S.; Elias, L.L.K.; Resstel, L.B.M. & Antunes-Rodrigues, J. Time-course of neuroendocrine changes and its correlation with hypertension induced by ethanol consumption. Alcohol Alcohol., 48(4): 495-504, 2013.

  9. Deolindo, M.V.; Reis, D.G.; Crestani, C.C.; Tavares, R.F.; Resstel, L.B.M. & Corrêa, F.M.A. NMDA receptors in the lateral hypothalamus have an inhibitory influence on the tachycardiac response to acute restraint stress in rats. Eur. J. Neurosci., 38(3): 2374-2381, 2013.

  10. Ferreira-Junior, N.C.; Fedoce, A.G.; Alves, F.H.F. & Resstel, L.B.M. Medial prefrontal cortex N-methyl-D-aspartate receptor/nitric oxide/cyclic guanosine monophosphate pathway modulates both tachycardic and bradycardic baroreflex responses. J. Neurosci. Res., 91(10): 1338-1348, 2013.

  11. Gomes, F.V.; Alves, F.H.F.; Guimarães, F.S.; Corrêa, F.M.A.; Resstel, L.B.M. & Crestani, C.C. Cannabidiol administration into the bed nucleus of the stria terminalis alters cardiovascular responses induced by acute restraint stress through 5-HT1A receptor. Eur. Neuropsychopharmacol., 23(9): 1096-1104, 2013.

  12. Lisboa, S.F.; Magesto, A.C.; Aguiar, J.C.; Resstel, L.B.M. & Guimarães, F.S. Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats. Neuropharmacol., 75: 86-94, 2013.

  13. Nagai, M.M.; Gomes, F.V.; Crestani, C.C.; Resstel, L.B.M. & Joca, S. R. Noradrenergic neurotransmission within the bed nucleus of the stria terminalis modulates the retention of immobility in the rat forced swimming test. Behav. Pharmacol., 24(3): 214-221,2013.

  14. Santini, C.O.; Fassini, A.; Scopinho, A.A.; Busnardo, C.; Corrêa, F.M.A. & Resstel, L.B.M. The ventral hippocampus NMDA receptor/nitric oxide/guanylate cyclase pathway modulates cardiovascular responses in rats. Auton. Neurosci.: Basic & Clin., 177(2): 244-252, 2013.

  15. Scopinho, A.A.; Lisboa, S.F.S.; Guimarães, F.S.; Corrêa, F.M.A.; Resstel, L.B.M. & Joca, S.R.L. Dorsal and ventral hippocampus modulate autonomic responses but not behavioral consequences associated to acute restraint stress in rats. PLoS One, 8(10): e77750, 2013.

  16. Terzian, A.L.; Dos Reis, D.G.; Guimarães, F.S.; Corrêa, F.M.A. & Resstel, L.B.M. Medial prefrontal cortex Transient Receptor Potential Vanilloid Type 1 (TRPV1) in the expression of contextual fear conditioning in Wistar rats. Psychopharmacol. (Berl)., 231(1): 149-157, 2013.

Prof. Dr. Norberto Cysne Coimbra

  1. Bertolino, G.; De Araujo, F.L.B.; Souza, H.C.D.; Coimbra, N.C. & De Araujo, J.E. Neuropathology and behavioral impairments after bilateral global ischemia surgery and exposure to static magnetic field: Evidence in the motor cortex, the hippocampal CA1 region and the neostriatum. Int. J. Radiat. Biol., 89(8): 595-601, 2013.

  2. Biagioni, A.F.; De Freitas, R.L.; Da Silva, J.A.; De Oliveira, R.C.; De Oliveira, R.; Alves, V.M. & Coimbra, N.C. Serotonergic neural links from the dorsal raphe nucleus modulate defensive behaviours organised by the dorsomedial hypothalamus and the elaboration of fear-induced antinociception via locus coeruleus pathways. Neuropharmacol., 67: 379-394, 2013.

  3. Da Silva, J.A.; De Freitas, R.L.; Eichenberger, G.C.D.; Padovan, C.M. & Coimbra, N.C. Chemical neuroanatomical and psychopharmacological evidence that κ receptor-mediated endogenous opioid peptide neurotransmission in the dorsal and ventral mesencephalon modulates panic-like behaviour. Eur. J. Pharmacol., 698(1-3): 235-245, 2013.

  4. Da Silva, L.FS..; Coimbra, N.C. & Menescal-de-Oliveira, L. Rostral ventromedial medulla connections in Cavia porcellus and their relation with tonic immobility defensive behavior: A biotinylated dextran amine neurotracing study. Neurosci. Lett., 535: 116-121, 2013.

  5. De Freitas, R.L.; Bolognesi, L.I.; Twardowschy, A.; Corrêa, F.M.A.; Sibson, N. R. & Coimbra, N.C. Neuroanatomical and neuropharmacological approaches to postictal antinociception-related prosencephalic neurons: the role of muscarinic and nicotinic cholinergic receptors. Brain Behav., 3(3): 286-301, 2013.

  6. De Freitas, R.L.; Salgado-Rohner, C.J.; Hallak, J.E.C.; Crippa, J.A.S. & Coimbra, N.C. Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid CB1 receptor. Int. J. Neuropsychopharmacol., 16(8): 1781-1798, 2013.

  7. Twardowschy, A.; Castiblanco-Urbina, M.A.; Uribe-Marino, A.; Biagioni, A.F.; Salgado-Rohner, C.J.; Crippa, J.A.S. & Coimbra, N.C. The role of 5-HT1A receptors in the anti-aversive effects of cannabidiol on panic attack-like behaviors evoked in the presence of the wild snake Epicrates cenchria crassus (Reptilia, Boidae). J. Psychopharmacol., 27(12): 1149-1159, 2013.

  8. Roncon, C.M.; Biesdorf, C.; Coimbra, N.C.; Audi, E.A.; Zangrossi, H., Jr. & Graeff, F.G.: Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and µ-receptors. J. Psychopharmacol., 27(12): 1141-1148, 2013.

Profa. Dra. Rita de Cássia Aleixo Tostes Passaglia

  1. Carvalho-de-Souza, J.L.; Varanda, W.A.; Tostes, R.C. & Chignalia, A.Z. BK channels in cardiovascular diseases and aging. Aging Dis., 4(1): 38-49, 2013.

  2. Carrillo-Sepulveda, M.A.; Ceravolo, G.S.; Furstenau, C.R.; Monteiro, P.S.; Bruno-Fortes, Z.; Carvalho, M.H.; Laurindo, F.R.; Tostes, R.C.; Webb, R.C. & Barreto-Chaves, M.L.M. Emerging role of angiotensin type 2 receptor (AT2R)/Akt/NO pathway in vascular smooth muscle cell in the hyperthyroidism. PLoS ONE, 8(4): e61982, 9 pages, 2013.

  3. Ceravolo, G.S.; Filgueira, F.P.; Costa, T.J.; Lobato, N.S.; Chignalia, A.Z.; Araujo, P.X.; Tostes, R.C.; Dantar, A.P.; Fortes, Z.B. & Carvalho, M.H.C. Conjugated equine estrogen treatment corrected the exacerbated aorta oxidative stress in ovariectomized spontaneously hypertensive rats. Steroids, 78(3): 341-346, 2013.

  4. Chiao, C-W.; da Silva-Santos, J.E.; Giachini, F.R.; Tostes, R.C.; Su, M.J. & Webb, R.C. P2X7 receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction. Clin. Sci. (Lond), 125(3): 131-141, 2013.

  5. Labazi, H.; Wynne, B.M.; Tostes, R. & Webb, R.C.: Metformin treatment improves erectile function in an angiotensin II model of erectile dysfunction. J. Sex. Med., 10(9): 2154-2164, 2013.

  6. Li, W.; Prakash, R.; Chawla, D.; Du, W.; Didion, S.P.; Filosa, J.A.; Zhang, Q.; Brann, D.W.; Lima, V.V.; Tostes, R.C. & Ergul, A. Early effects of high-fat diet on neurovascular function and focal ischemic brain injury. Am. J. Physiol. Regul. Integr. Comp. Physiol., 304(11): R1001-R1008, 2013.

  7. Lobato, N.S.; Filgueira, F.P.; Prakash, R.; Giachini, F.R.; Ergul, A.; Carvalho, M.H.C.; Webb, R.C.; Tostes, R.C. & Fortes, Z.B. Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. PLoS ONE, 8(5): e63449, 11 pages, 2013.

  8. Tezini, G.C.S.V.; Becari, C.; Zanotto, C.Z.; Salgado, M.C.O.; Passaglia, R.C.A.T. & Souza, H.C.D. Ageing is the main determinant of haemodynamics and autonomic cardiac changes observed in post-menopausal female rats. Auton. Neurosc.: Basic & Clinical, 174: 36-41, 2013.

Prof. Dr. Thiago Mattar Cunha

  1. Carreira, E.U.; Carregaro, V.; Teixeira, M.M.; Moriconi, A.; Aramini, A.; Verri Jr., W.A.; Ferreira, S.H.; Cunha, F.Q. & Cunha, T.M. Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain. Eur. J. Pain, 17(5): 654-663, 2013.

  2. De Luca, B.; Xavier-Elsas, P.; Barradas, M.; Luz, R. A.; Queto, T.; Jones, C.; Arruda, M. A.; Cunha, T. M.; Cunha, F. Q. & Gaspar-Elsas, M. I. Essential Roles of PKA, iNOS, CD95/CD95L, and Terminal Caspases in Suppression of Eosinopoiesis by PGE2 and Other cAMP-Elevating Agents. Scientific World Journal., 2013, 208705 (Electronic).

  3. Donate, P.B.; Fornari, T.A.; Macedo, C.; Cunha, T.M.; Nascimento, D.C.B.; Sakamoto-Hojo, E.T.; Donadi, E.A.; Cunha, F.Q. & Passos, G.A. T cell post-transcriptional Mirna-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis. PloS ONE, 8(1): e54803, 2013.

  4. Figueiredo, J.; Ferreira, A.E.; Silva, R.L.; Ulloa, L.; Grieco, P.; Cunha, T.M.; Ferreira, S.H.; Cunha, F.Q. & Kanashiro, A. NDP-MSH inhibits neutrophil migration through nicotinic and adrenergic receptors in experimental peritonitis. Naunyn-Schmiedeberg´s Arch. Pharmacol., 386(4): 311-318, 2013.

  5. Franchin, M.; Cunha, M.G.; Denny, C.; Napimoga, M.H.; Cunha, T.M.; Bueno-Silva, B.; Alencar, S.M.; Ikegaki, M. & Rosalen, P.L. Bioactive fraction of geopropolis from Melipona scutellaris decreases neutrophils migration in the inflammatory process: Involvement of nitric oxide pathway. Evid. Based Complement Alternat. Med., 2013: Article ID 907041, 9 pages, 2013.

  6. Guerrero, A.T.; Zaperlon, A.C.; Vieira, S.M.; Pinto, L.G.; Ferreira, S.H.; Cunha, F.Q.; Verri Jr., W.A.; & Cunha, T.M. The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia. Naunyn-Schmiedeberg´s Arch. Pharmacol., 386(1): 51-59, 2013.

  7. Hohmann, M. S.; Cardoso, R. D.; Pinho-Ribeiro, F. A.; Crespigio, J.; Cunha, T. M.; Alves-Filho, J. C.; Da Silva, R. V.; Pinge-Filho, P.; Ferreira, S. H.; Cunha, F. Q.; Casagrande, R. & Verri, W. A., Jr.: 5-lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality. Biomed. Res. Int., 2013 627046. (Electronic).

  8. Magro, D.A.C.; Hohmann, M.S.N.; Mizokami, S.S.; Cunha, T.M.; Alves-Filho, J.C.; Casagrande, R.; Ferreira, S.H.; Liew, F.Y.; Cunha, F.Q. & Verri Jr, W.A. An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice. Braz. J. Med. Biol. Res., 46(7): 601-606, 2013.

  9. Santos, D.S.; Marta, I.E.R.; Cárnio, E.C.; Quadros, A.U.; Cunha, T.M. & Carvalho, E.C. Using na experimental model for the study of therapeutic touch. Rev. Latino-Am. Enfermagem, 21(1): 442-449, 2013.

  10. Souza, G.R.; Talbot, J.; Lotufo, C.M.; Cunha, F.Q.; Cunha, T.M. & Ferreira, S.H. Fractalkine mediates inflammatory pain through activation of satellite glial cells. Proc. Natl. Acad. Sci. USA., 110(27): 11193-11198, 2013.

  11. Vercelino, R.; Cunha, T.M.; Ferreira, E.S.; Cunha, F.Q.; Ferreira, S.H. & Oliveira, M.G. Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel. J. Mater Sci: Mater Med., 24(9): 2157-2169, 2013.

  12. Zarpelon, A. C.; Cunha, T. M.; Alves-Filho, J. C.; Pinto, L. G.; Ferreira, S. H.; Mcinnes, I. B.; Xu, D.; Liew, F. Y.; Cunha, F. Q. & Verri, W. A., Jr. IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2. Br. J. Pharmacol., 169(1): 90-101, 2013.

  13. Zarpelon, A.C.; Souza, G.R.; Cunha, T.M.; Schivo, I.R.S.; Marchesi, M.; Casagrande, R.; Pinge-Filho, P.; Cunha, F.Q.; Ferreira, S.H.; Miranda, K.M. & Verri Jr., W.A. The nitroxyl donor, Angeli´s salt, inhibits inflammatory hyperalgesia in rats. Neuropharmacol., 71: 1-9, 2013.

Prof. Dr. Sérgio Henrique Ferreira

  1. Abrantes, V.E.F.; Matias da Rocha, B.A.; Batista da Nóbrega, R.; Silva-Filho, J. C.; Teixeira, C.S.; Cavada, B.S.; Gadelha, C.A.A.; Ferreira, S. H.; Figueiredo, J.G.; Santi-Gadelha, T. & Delatorre, P. Molecular modeling of lectin-like protein from Acácia farnesiana reveals a possible anti-inflammatory mechanism in carrageenan-induced inflammation. Biomed. Res. Int., 2013: Article ID 253483, 9 pages.

  2. Araldi, D.; Ferrari, L.F.; Lotufo, C.M.; Vieira, A.S.; Athié, M.C.P.; Figueiredo, J.G.; Duarte, D.B.; Tambeli, C.H.; Ferreira, S. H. & Parada, C.A. Peripheral inflammatory hyperalgesia depends on the COX increase in the dorsal root ganglion. Proc. Natl. Acad. Sci. USA, 110(9): 3603-3608, 2013.

  3. Carreira, E.U.; Carregaro, V.; Teixeira, M.M.; Moriconi, A.; Aramini, A.; Verri Jr., W.A.; Ferreira, S.H.; Cunha, F.Q. & Cunha, T.M. Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain. Eur. J. Pain, 17(5): 654-663, 2013.

  4. Czaikoski, P.G.; Nascimento, D.C.; Sônego, F.; de Freitas, A.; Turato, W.M.; de Carvalho, M.A.; Santos, R.S.; de Oliveira, G.P.; dos Santos Samary, C.; Tefé-Silva, C.; Alves-Filho, J.C.; Ferreira, S.H.; Rossi, M.A.; Rocco, P.R.; Spiller, F. & Cunha, F.Q. Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis. Shock, 39(4): 389-396, 2013.

  5. Figueiredo, J.; Ferreira, A.E.; Silva, R.L.; Ulloa, L.; Grieco, P.; Cunha, T.M.; Ferreira, S.H.; Cunha, F.Q. & Kanashiro, A. NDP-MSH inhibits neutrophil migration through nicotinic and adrenergic receptors in experimental peritonitis. Naunyn-Schmiedeberg´s Arch. Pharmacol., 386(4): 311-318, 2013.

  6. Guerrero, A.T.; Zaperlon, A.C.; Vieira, S.M.; Pinto, L.G.; Ferreira, S.H.; Cunha, F.Q.; Verri Jr., W.A.; & Cunha, T.M. The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia. Naunyn-Schmiedeberg´s Arch. Pharmacol., 386(1): 51-59, 2013.

  7. Magro, D.A.C.; Hohmann, M.S.N.; Mizokami, S.S.; Cunha, T.M.; Alves-Filho, J.C.; Casagrande, R.; Ferreira, S.H.; Liew, F.Y.; Cunha, F.Q. & Verri Jr, W.A. An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice. Braz. J. Med. Biol. Res., 46(7): 601-606, 2013.

  8. Souza, G.R.; Talbot, J.; Lotufo, C.M.; Cunha, F.Q.; Cunha, T.M. & Ferreira, S.H. Fractalkine mediates inflammatory pain through activation of satellite glial cells. Proc. Natl. Acad. Sci. USA, 110(27): 11193-11198, 2013.

  9. Vercelino, R.; Cunha, T.M.; Ferreira, E.S.; Cunha, F.Q.; Ferreira, S.H. & Oliveira, M.G. Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel. J. Mater Sci: Mater Med., 24(9): 2157-2169, 2013.

  10. Villarreal, C.F.; Funez, M.I.; Cunha, F.Q.; Parada, C.A. & Ferreira, S.H. The long-lasting sensitization of primary afferent nociceptors induced by inflammation involves prostanoid and dopaminergic systems in mice. Pharmacol. Biochem. Behav., 103(3): 678-683, 2013.

  11. Zarpelon, A.C.; Souza, G.R.; Cunha, T.M.; Schivo, I.R.S.; Marchesi, M.; Casagrande, R.; Pinge-Filho, P.; Cunha, F.Q.; Ferreira, S.H.; Miranda, K.M. & Verri Jr., W.A. The nitroxyl donor, Angeli´s salt, inhibits inflammatory hyperalgesia in rats. Neuropharmacol., 71: 1-9, 2013.

Prof. Dr. Wiliam Alves do Prado

  1. Dias, Q.M.; Rossaneis, A.C.; Fais, R.S. & Prado, W.A. An improved experimental model for peripheral neuropathy in rats. Braz. J. Med. Biol. Res., 46(3): 253-256, 2013.

  2. Fais, R.S.; Reis, G.M.; Dias, Q.M.; Rossaneis, A.C.; Silveira, J.W.S. & Prado, W.A. Amitriptyline prolongs the antihyperalgesic effect of 2Hz electroacupuncture in mononeuropathic rats. Acupuncture and Related Therapies, 1: 20-26, 2013.

  3. Genaro, K.; Juliano, M.A.; Prado, W.A.; Brandão, M.L. & Martins, A.R. Effects of angiotensin (5-8) microinfusions into the ventrolateral periaqueductal gray on defensive behaviors in rats. Behav. Brain Res., 256: 537-544, 2013.

  4. Guethe, L.M.; Pelegrini-da-Silva, A.; Borelli, K.G.; Juliano, M.A.; Pelosi, G.G.; Pesquero, J.B.; Silva, C.L.M.; Corrêa, F.M.A.; Murad, F.; Prado, W.A. & Martins, A.R. Angiotensin (5-8) modulates nociception at the rat periaqueductal gray via the NO-sGC pathway and an endogenous opioid. Neuroscience 231: 315-327, 2013.

  5. Silva, J.R.T.; Silva, M.L. & Prado, W.A. Spinal mediatioon of descending pain inhibitorsy mechanisms activated by 2/100-Hz electroacupunture in the rata tail-flick test. Acupunture and Related Therapies, 1: 15-19, 2013.

  6. Silva, J.R.T.; Silva, M.L. & Prado, W.A. Electroacupuncture at 2/100 Hz activates antinociceptive spinal mechanisms different from those activated by electroacupuncture at 2 and 100 Hz in responder rats. Evid Based Complement Alternat Med. 2013; 2013: 205316. Published online 2013 September 16. doi: 10.1155/2013/205316 (Não existe no. de página por ser on line).

  7. Silva, M.L.; Silva, J.R.T. & Prado, W.A. Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the anterior pretectal nucleus. Life Sci., 93(20): 742-754, 2013.